Early-stage, indolent, non-Hodgkin lymphoma (stages 1 and 2)
- Localised radiotherapy alone is used to treat patients with early stage or indolent non-Hodgkin lymphoma. This is generally very successful.
Late-stage, indolent, non-Hodgkin lymphoma (stages 3 and 4)
- At first many patient may be managed with a ‘watch and wait’ approach
- After this they will receive a mixture of chemotherapy drugs as well as some radiotherapy.
Relapsed indolent non-Hodgkin lymphoma
- Additional chemotherapy is used to treat patients with indolent non-Hodgkin lymphoma that has recurred
Early-stage aggressive non-Hodgkin lymphoma
- Patients are treated with several courses of a mixture of chemotherapy drugs.
- This limits the chance that patients will develop resistance to any of the drugs and also reduces the side effects.
- This may be followed by radiotherapy directed at the affected lymph nodes.
Late-stage aggressive non-Hodgkin lymphoma
- Patients are also treated with several courses of chemotherapy drugs
- Monoclonal antibody therapy, which targets cancer cells directly, may be used in combination with chemotherapy.
Relapsed aggressive non-Hodgkin lymphoma
- Additional high dose chemotherapy is used to treat patients with aggressive non-Hodgkin lymphoma whose disease has returned even after having completed treatment.
- Some patient may benefit from a stem cell transplant